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Part II of "Levodopa - if this is the "gold standard," we are in trouble"

basically, 40 years of research into fixing levodopa's problems has reduced 
nausea, reduced the frequency of dosing, and added less than an hour of on time 
per day - oh, and it has also resulted in a four-fold increase in the risk of 
dyskinesias.

be sure to read the package insert if you are contemplating starting a levodopa 
product - incidence of dyskinesias is 60% higher with sinemet than with 
levodopa (you would actually have to go to pubmed for that info because sinemet 
came out so long ago statistics like that have long since been revised out of 
the product insert); the incidence of dyskinesias is 35% higher with sinemet cr 
than with sinemet; and the incidence of dyskinesias is 75% higher with stalevo 
than with sinemet cr.

that is not what i call progress.


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