Re: Question regarding Requip

[kbachn <kbachn@xxxxxxxxxxxx>]

Thanks much for all your prompt replies.


----- Original Message -----
From: "Arnie Kuzmack" <Arnie@xxxxxxxxxxx>
To: <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
Sent: Monday, January 01, 2007 11:18 AM
Subject: Re: Question regarding Requip


> It is common with all dopamine agonists.  I have taken 3 of them
> over the years (Requip, Mirapex, and a Lisuride transdermal patch
> in a clinical trial) and observed it with all 3.  It is
> particularly serious if you drive and can be a problem in a work
> or social situation.
>
> You can take drugs to counteract it.  I found Provigil was
> particularly effective, but it cost $3,000 a year and my insurace
> would not cover it.  I am now taking Ritalin and it works pretty
> well.
>
> Here are several abstracts of articles in the medical literature
> on the subject.  Abstracts can be found on PubMed:
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=journals
>
> Ondo WG, Fayle R, Atassi F, Jankovic J.
> Modafinil for daytime somnolence in Parkinson's disease: double
> blind, placebo controlled parallel trial.
> J Neurol Neurosurg Psychiatry. 2005 Dec;76(12):1636-9.
> PMID: 16291885
>
> Comella CL.
> Sleep disturbances and excessive daytime sleepiness in Parkinson
> disease: an overview.
> J Neural Transm Suppl. 2006;(70):349-55. Review.
> PMID: 17017552 [PubMed - indexed for MEDLINE]
>
> Gjerstad MD, Alves G, Wentzel-Larsen T, Aarsland D, Larsen JP.
> Excessive daytime sleepiness in Parkinson disease: is it the
> drugs or the disease?
> Neurology. 2006 Sep 12;67(5):853-8.
> PMID: 16966550 [PubMed - indexed for MEDLINE]
>
> Borek LL, Kohn R, Friedman JH.
> Mood and sleep in Parkinson's disease.
> J Clin Psychiatry. 2006 Jun;67(6):958-63.
> PMID: 16848656 [PubMed - in process]
>
> Monaca C, Duhamel A, Jacquesson JM, Ozsancak C, Destee A, Guieu
> JD, Defebvre L, Derambure P.
> Vigilance troubles in Parkinson's disease: a subjective and
> objective polysomnographic study.
> Sleep Med. 2006 Aug;7(5):448-53. Epub 2006 Jun 5.
> PMID: 16740409 [PubMed - indexed for MEDLINE]
>
> Ferreira JJ, Desboeuf K, Galitzky M, Thalamas C, Brefel-Courbon
> C, Fabre N, Senard JM, Montastruc JL, Sampaio C, Rascol O.
> Sleep disruption, daytime somnolence and 'sleep attacks' in
> Parkinson's disease: a clinical survey in PD patients and age-
> matched healthy volunteers.
> Eur J Neurol. 2006 Mar;13(3):209-14.
> PMID: 16618334 [PubMed - indexed for MEDLINE]
>
> Rye DB.
> Excessive daytime sleepiness and unintended sleep in Parkinson's
> disease.
> Curr Neurol Neurosci Rep. 2006 Mar;6(2):169-76. Review.
> PMID: 16522272 [PubMed - indexed for MEDLINE]
>
> Wegelin J, McNamara P, Durso R, Brown A, McLaren D.
> Correlates of excessive daytime sleepiness in Parkinson's
> disease.
> Parkinsonism Relat Disord. 2005 Nov;11(7):441-8. Epub 2005 Sep 9.
> PMID: 16154796 [PubMed - indexed for MEDLINE]
>
> Moller JC, Rethfeldt M, Korner Y, Stiasny-Kolster K, Cassel W,
> Meindorfner C, Rissling I, Kruger HP, Oertel WH.
> Daytime sleep latency in medication-matched Parkinsonian
> patients with and without sudden onset of sleep.
> Mov Disord. 2005 Dec;20(12):1620-2.
> PMID: 16078226 [PubMed - indexed for MEDLINE]
>
> Arnulf I.
> Excessive daytime sleepiness in parkinsonism.
> Sleep Med Rev. 2005 Jun;9(3):185-200. Epub 2005 Apr 26. Review.
> PMID: 15893249 [PubMed - indexed for MEDLINE]
>
> Meindorfner C, Korner Y, Moller JC, Stiasny-Kolster K, Oertel WH,
> Kruger HP.
> Driving in Parkinson's disease: mobility, accidents, and sudden
> onset of sleep at the wheel.
> Mov Disord. 2005 Jul;20(7):832-42.
> PMID: 15726539 [PubMed - indexed for MEDLINE]
>
> Kaynak D, Kiziltan G, Kaynak H, Benbir G, Uysal O.
> Sleep and sleepiness in patients with Parkinson's disease before
> and after dopaminergic treatment.
> Eur J Neurol. 2005 Mar;12(3):199-207.
> PMID: 15693809 [PubMed - indexed for MEDLINE]
>
> Romigi A, Brusa L, Marciani MG, Pierantozzi M, Placidi F, Izzi F,
> Sperli F, Testa F, Stanzione P.
> Sleep episodes and daytime somnolence as result of individual
> susceptibility to different dopaminergic drugs in a PD patient: a
> polysomnographic  study.
> J Neurol Sci. 2005 Jan 15;228(1):7-10. Epub 2004 Nov 10.
> PMID: 15607203 [PubMed - indexed for MEDLINE]
>
>
> ----- Original Message -----
> From: "M.Schild" <mmoo@xxxxxxxxxxxxxxxx>
> To: <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
> Sent: Monday, January 01, 2007 2:53 AM
> Subject: Re: Question regarding Requip
>
>
> > I justed started taking Requip to supplement the levodopa. I
> > experienced a
> > lot of drowsiness that last for 1.5 hrs plus. Wondering if this
> > is normal.
>
>
> I think a lot of people experience somnolence with Requip.
> Sometimes it goes,
> sometimes not
> maryse cg JOhn 77,17
>
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