Parkinsn's Email List Message

Posting to the Parkinsn List is a benefit of Subscription

[Message Prev][Message Next][Thread Prev][Thread Next][Message Index][Thread Index]

Total sleep deprivation and Parkinson disease


Mail converted by MHonArc 2.6.10
Site Hosting donated by He.net
&
Grant from The Parkinson Alliance 

Total sleep deprivation and Parkinson disease
Bertolucci PH, Andrade LA, Lima JG, Carlini EA
Arq Neuropsiquiatr 45(3) 224-230 (1987)
Twelve Parkinson disease (PD) patients were submitted to a single night of
total sleep deprivation (SD). Disease duration had a median of 5.1 years and
all were using either anticholinergic or L-Dopa or the combination of both
drugs. After SD there was an improvement of rigidity, bradykinesia, gait and
posture disturbances and functional disability that remained significant for
2 weeks. No effect was observed on tremor. Concerning depressive symptoms, a
significant difference was noted, that remained for one week. These results
suggest that SD may be an useful procedure to improve PD symptomatology. It
is discussed a possible change of dopaminergic receptors, induced by SD, to
explain the improvement.

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:listserv@xxxxxxxxxxxxxxxxxxxx
In the body of the message put: signoff parkinsn