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Re: Hopes rise over Parkinson's


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this is very interesting. anyone knows the difference btw this gene therapy
and the Ceregene one.

upon reading the website, an article mentioned that they only recruite late
stages of parkinson (undersandable) and those WITHOUT dyskinisea ( curious
as to why this is so, does it mean they suspect or already know that this
treatment wont work with those with dyskinesea ).

any insight?

Thank You and Regards, Ken


----- Original Message -----
From: "M.Schild" <mmoo@xxxxxxxxxxxxxxxx>
To: <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
Sent: Saturday, December 15, 2007 2:47 AM
Subject: Hopes rise over Parkinson's


Hopes rise over Parkinson's

Scientists at an Oxford biotech firm are hoping they have made a
breakthrough
in the search for an effective Parkinson's Disease treatment.
Trials on the ProSavin gene therapy product, which has been developed by
Oxford Biomedica based at the Oxford Science Park, have started in France,
with experts confident of success.
Chief executive Prof Alan Kingsman said: "The product could represent a
fundamentally new approach for the treatment of Parkinson's Disease and
could
significantly expand the worldwide market for existing therapies."


He said the clinical trial followed more than 10 years of research.
Parkinson's disease is caused by the degeneration of dopamine-producing
nerve
cells, leading to impaired movement.
ProSavin uses gene therapy to restore dopamine production in the brain.
Initial tests have shown almost complete recovery of movement and other
behaviour with a single treatment effective for at least two years.
Current surgical approaches to treatment require the destruction of brain
tissue or the use of electrodes to stimulate the brain, both of which have
side effects.
4:51pm Friday 14th December 2007

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