Re: Sinemet vs. Mirapex, etc.

["M.Schild" <mmoo@xxxxxxxxxxxxxxxx>]

> I am 65, diagnosed last year, just starting Sinemet. My neurologist
> tells me that Sinemet does not induce on-off symptoms or dyskinesias,
> and that those would occur with or without it as a result of the natural
> progression of PD. This issue arose in discussion of dopamine agonists
> pro's and con's and my reluctance to start down the Sinemet road without
> knowing where it would lead. She says that favorable reviews of DA's are
> due largely to promotional efforts of pharmaceutical companies. I would
> be grateful for any thoughts and insights on this.


I think she is right about the agonists but on-off  symptoms and dyskinesias 
are a product of dopatherapy.  Sinemet or agonists.
Here in France, the new guidines are  not to prescribe agonists after 65-70.
maryse cg John 79,18

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