Re: 2000 yr old case of PD

[rayilynlee <rayilynlee@xxxxxxx>]

Murray and Steve

I blame my grandfather for my PD.  He was a disagreeable guy so it helps to 
have someone to blame, I think.

However, nobody deserves this disease.

Ray

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
rbrown@xxxxxxxxx

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From: "Steve Rack" <srack@xxxxxxxxx>
Sent: Tuesday, March 17, 2009 2:18 PM
To: <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
Subject: Re: 2000 yr old case of PD

> > PARKINSON'S DISEASE NEWS
> > from Viartis
> >
> > 16th March 2009 - New research
> > 2000 YEAR OLD CASE OF PARKINSON'S DISEASE
> >
> > Neurogenetics [2009] Mar 13. [Epub ahead of print] (Bar-Shira A, Hutter 
> > CM, Giladi N, Zabetian CP, Orr-Urtreger A.) Complete abstract
> >
> > It is often claimed that Parkinson's Disease was discovered in 1817 by 
> > James Parkinson. However, there have been descriptions and treatments of 
> > Parkinson's Disease since ancient times. For more information go to the 
> > History of Parkinson's Disease. There is a genetic mutation called LRRK2 
> > G2019S that increases the likelihood of Parkinson's Disease. It is most 
> > common amongst Ashkenazi Jews. Ashkenazi Jews descend from Jews in 
> > medieval Germany. It was found that Ashkenazi Jews who had Parkinson's 
> > Disease due to this genetic mutation had a common ancestor who lived 
> > nearly 2000 years ago. Their ancestor, who would have probably had 
> > Parkinson's Disease, lived approximately 1,830 (1,560-2,160) years ago, 
> > around the second century A.D., after the second Jewish Diaspora.
>
> Thanks Ray.
>  Now I have someone to point a finger at. My mom's father emigrated from 
> Hamburg. He died young so we will never know if he had Pd. Now, for what 
> it's worth, we can blame Grandpa for Mom's and my Pd.
> I just reread this and it seems I've let some bitterness out. Maybe I'd 
> rather I didn't know about this. Another learning experience I suppose.
> --
> Steve in VT
>
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