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MODAFINIL FOR FATIGUE


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MODAFINIL FOR FATIGUE IN PARKINSON'S DISEASE 
Clinical Neuropharmacology [2009] 32 (6) : 305-310 (Lou JS, Dimitrova DM, Park 
BS, Johnson SC, Eaton R, Arnold G, Nutt JG.) Complete abstract
                                                                                
                                                                                
                 
Fatigue is a major symptom in Parkinson disease. It is associated with reduced 
activity and lower quality of life. Modafinil has been considered for use in 
the treatment of fatigue in Parkinson's Disease due to its ability to release 
dopamine. For more information go to Modafinil. A study has determined whether 
Modafinil improves subjective fatigue and physical fatigability in Parkinson's 
Disease. After a month Modafinil made no difference. After two months 
Modafinil helped to some extent with physical fatigue. However for fatigue 
generally it still had no effect. The primary problem in Parkinson's Disease 
is the inability to produce optimal amounts of dopamine. The reason for the 
ineffectiveness of Modafinil in Parkinson's Disease may be due to it only 
releasing dopamine. It doesn't form any additional dopamine in order for more 
to be released. In order to refer to this article on its own click here. 

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